This medication will lead to constipation. If you don't Have a very bowel motion for 3 days, contact your treatment staff.
It really is not known if this medication passes into breast milk. Having said that, it could possibly have undesirable results with a nursing infant. Talk to your medical doctor ahead of breastfeeding.
The codeine and promethazine in Promethazine HCl and Codeine Phosphate Oral Answer may improve the frequency of seizures in sufferers with seizure disorders, and should boost the chance of seizures happening in other clinical options related to seizures.
Codeine in oral therapeutic dosage won't ordinarily exert important results on the cardiovascular program.
Promethazine HCl and Codeine Phosphate Oral Answer is indicated with the short term reduction of coughs and upper respiratory signs or symptoms related to allergy or maybe the widespread chilly in individuals 18 many years of age and more mature.
This medication may well interfere with specified lab tests (for instance some pregnancy checks, blood sugar tests, amylase/lipase levels), maybe creating Phony exam success. Ensure that lab staff and all your Physicians know you employ this drug.
, ritonavir) or discontinuation of a cytochrome P450 3A4 inducer which include rifampin, carbamazepine, and phenytoin, might result in a rise in codeine plasma concentrations with subsequently better metabolism by cytochrome P450 2D6, causing better morphine levels, which could maximize or lengthen adverse reactions and should induce perhaps deadly respiratory despair.
Although antihistamines have been identified to create fetal mortality in rodents, the pharmacological outcomes of histamine in the rodent do not parallel All those in male. There isn't any satisfactory and well-managed scientific tests of promethazine in pregnant Gals.
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Codeine Carcinogenicity research were being conducted with codeine. Two-calendar year experiments in F344/N rats and B6C3F1 mice were performed to evaluate the carcinogenic prospective of codeine. No proof of tumorigenicity was noticed in male and feminine rats at codeine dietary doses approximately 70 and 80 mg/kg/working day (somewhere around equivalent to 15 and twenty moments, the MRHD over a mg/m2 foundation, respectively).
Retailer at place temperature faraway from light-weight and moisture. Usually do not retailer in the toilet. Usually do not freeze. Retain all drugs faraway from young children and Promethazine codeine syrup Animals.
This product or service may well consist of inactive components, that may trigger allergic reactions or other issues. Speak with your pharmacist for more details.
Sedating medicines may possibly lead to confusion and more than-sedation while in the elderly; aged people typically need to be started on lower doses of promethazine with codeine syrup and noticed carefully.
To aid prevent withdrawal, your medical doctor could reduce your dose gradually. Withdrawal is more very likely Should you have utilized this medication for a very long time (more than a few months) or in superior doses. Convey to your medical doctor or pharmacist at once When you've got withdrawal.